Nebbiolo grapes are grown primarily in the Piedmont region of Italy where they can produce great wines; outside of Piedmont, though, the grapes produce mediocre wines at best. Nebbiolo has complex flavors and aromas, including roses, cherries, truffles, and mints. There can even be hints of tar, tobacco, and leather. Other characteristics of wine made from Nebbiolo grapes include high tannins, high acidity, and high alcohol content. Nebbiolo wines take on orange tinges when they are aged.

Barbera is the third most widely planted red grape variety in Italy though it is most common in the Asti and Alba regions. Barbera grapes produce rich, red wines with strong fruit flavors and aromas, especially black cherry. Other characteristics of wines made with Barbera grapes include low, mild tannins and high acidity which produces a crisp taste.

Sangiovese grapes are common in the Tuscany, are the most planted red grape variety in Italy, and are popular for the production of Chianti wines. Sangiovese flavors and aromas are strong in fruit, especially tart cherries, with floral notes.

Other characteristics of wines made from Sangiovese grapes include firm tannins and high acidity. The exact flavors and aromas of any particular Sangiovese wine depends heavily on where the grapes are grown and how the wine maker creates the wine.

Grenache grapes originated in Spain where it is called Garnacha, but Grenache is the name by which the grapes and resulting wine are most commonly known. Grenache wines have flavors and aromas of strong fruit, raspberries, and a bit of spice.

Other characteristics of wines made from Grenache grapes include weak colors, soft tannins, and high alcohol content. Grenache tends to be most closely associated with the southern French region of Rhone where it is grown widely.